This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state ...

Cardiac fibroblasts play a critical role throughout the various phases of murine heart development ranging from the embryonic to the neonatal stage.

GPCRs (G-protein [guanine nucleotide-binding protein]–coupled receptors) play a central physiological role in the regulation of cardiac function in both health and disease and thus represent one of ...

The calcium-responsive molecule, calcineurin, has been well characterized to play a causal role in pathological cardiac hypertrophy over the past decade. However, the intrinsic negative regulation of ...

UCLA researchers found that two proteins doctors use to check for heart damage can also predict cancer years before symptoms appear.