In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab ...

In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable "disordered" proteins.

An AI called AlphaFold predicted structures for nearly every protein known to science. Those predictions aren’t without limits, some researchers say.

There’s an age-old adage in biology: structure determines function. To understand the function of the myriad proteins that perform vital jobs in a healthy body—or malfunction in a diseased one ...

The ultimate aim of structural genomics is not to obtain the structures or models for all proteins, but to contribute to biology and medicine through functional annotation 4,5,6,7, and through ...

This means that the hydrophobic repulsive force stabilizes the folded protein structure. ... (2021, October 4). Restructuring biology: New study shows protein hydrophobic parts do not hate water.

AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve that problem, lives on.

Over the past two years, machine learning has revolutionized protein structure prediction. Now there's a similar revolution in protein design. Biologists show that machine learning can be used to ...

The prediction of protein structure with the use of artificial intelligence and machine learning (AI–ML) is poised to transform how and when three-dimensional (3D) biostructure information is ...

In a new preprint, the team behind the protein structure prediction software RoseTTAFold has announced a tool that expands the types of chemistry that protein designers using deep learning will be ...