Jacob E. Berchuck, MD, highlights novel findings pointing to androgen receptor signaling and Wnt pathway activation as key correlates of poor response to therapy.

Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new ...

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells.

Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function.

Fragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism, is caused by silencing of the Fmr1 gene, leading to a lack of the FMRP protein, which regulates protein ...

Acute alcohol exposure impairs CRF-induced cholinergic activity.

Corazonin bridges the brain's photoperiodic clock region and ovarian suppression in response to short-day signalsAs the days ...

Astegolimab is a fully human anti-ST2 monoclonal antibody designed to bind to the ST2 receptor and block the IL-33 signalling pathway.

LEO Pharma and Boehringer Ingelheim have entered into a partnership to commercialise and advance the development of ...

Dopamine is one of the most extensively studied chemical messengers in the human brain, and yet scientists are still figuring ...

KAIST researchers have uncovered how alcohol-induced liver inflammation begins: through glutamate signaling and a brain-like ...

Setmelanotide was associated with significant weight reduction among patients aged 4 years and older with acquired hypothalamic obesity.