However, a lack of understanding of how remyelination is stymied in the disease has hampered these efforts. Now, University at Buffalo researchers have found that a receptor called muscarinic type 3 ...

Remyelination, the spontaneous regeneration of the fatty insulator in the brain that keeps neurons communicating, has long been seen as crucial to the next big advance in treating multiple sclerosis ...

The neuroscientists identified a protein called eEF1A1 as a key factor in the process and found that eEF1A1 activated by acetylation prevents the remyelination process, but if eEF1A1 is ...

Or, say others, perhaps the LINGO pathway just isn't a strong enough modulator of the remyelination process. “Failure to show really solid overwhelming efficacy is never a surprise.

image: Remyelination in the spinal cord after experimental focal degradation of myelin sheaths, ... "First, we wanted to understand the process that blocks remyelination.

Researchers have revealed the molecular mechanism involved in the process of repair to damage of the myelin sheath.This achievement shows that it is possible to encourage the regeneration of the ...

For additional information please contact: Genevieve Maul, Office of Communications, University of Cambridge Tel: direct, 44-1223-765542, 44-1223-332300 ...

Remyelination is a natural regenerative process causing symptomatic improvement, but it is unfortunately restricted and inefficient in chronic demyelinating disorders 8.

During multiple sclerosis (MS), myelin is destroyed, leading to neurological deficits. Even though myelin can be restored through a process known as remyelination, this regenerative response largely ...

Researchers report what they call 'the first clinical study to show evidence of proof of biology for remyelination in multiple sclerosis': improved optic nerve conduction in optic neuritis.