The misshapen cells tend to block blood flow in the vessels, leading to frequent pain episodes, infections, and damage to organs.

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Danaher, a United States-headquartered life sciences conglomerate, announced a strategic partnership in Shanghai on Monday between its operating company Cytiva and CorrectSequence Therapeutics, a ...

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...

But I've come to find out Gwada negative now makes it 48 different blood types. We don’t hear about them because they’re so ...

An overview of World Sickle Cell Anemia Day 2025 and the global and local challenges of managing sickle cell disease.

So far in 2025, the Trump administration has cut more than $1 billion in NIH grants. That includes a study on sickle cell ...

Families of those who have sickle cell disease in the Philadelphia area are pushing for more research and a cure.

Columnist Oluwatosin Adesoye, a doctor, sorts through the difference between sickle cell anemia and sickle cell disease — and more.

Gabriella Ngang, of Farmington Hills, is one of three in Michigan to take part in a clinical trial of a new sickle cell ...

Sickle cell disease articles from across Nature Portfolio Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene ...

The most severe form of sickle cell disease, sickle cell anemia causes red blood cells to be sickle- or crescent-shaped, rather than a disc. That distortion causes the cells to get stuck in the ...