Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood.

Discover the current pipeline candidates advancing through the clinic for the treatment of sickle cell disease.

Columnist Oluwatosin Adesoye, a doctor, sorts through the difference between sickle cell anemia and sickle cell disease — and more.

The more Betsy Adler learned about her family's medical history, the more interested and concerned she became. Several of her first cousins had been treated for cancer, and three of her male ...

The misshapen cells tend to block blood flow in the vessels, leading to frequent pain episodes, infections, and damage to organs.