Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Discover the current pipeline candidates advancing through the clinic for the treatment of sickle cell disease.

Columnist Oluwatosin Adesoye, a doctor, sorts through the difference between sickle cell anemia and sickle cell disease — and more.

The more Betsy Adler learned about her family's medical history, the more interested and concerned she became. Several of her first cousins had been treated for cancer, and three of her male ...

The misshapen cells tend to block blood flow in the vessels, leading to frequent pain episodes, infections, and damage to organs.

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...

Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene, which leads to deformation of red blood cells. Deformed ...