NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's ...

In addition, germ cells require a specialized environment, or niche, provided by the supporting somatic cells in which to differentiate.

Germline gene therapy and somatic gene therapy are two quite different proposals, and the legitimate concerns and risks of the former should not be used to stall progress on the latter.

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the ...

Depending on the organism, these cells arrange themselves into a variety of tissues and organs, such as the gut, muscles, and sensory systems. While not all animals have each of these tissues, they do ...