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The 21c Museum Hotel St. Louis is now open in the heart of Downtown. This adaptive reuse project transformed the historic YMCA building, located at 1528 Locust and listed on the National Register of ...

The first thing you see when you enter the 21c Museum Hotel in St. Louis is a work of art I called The Orb. Its real name is almost certainly something else (I just googled it: it’s called O, and it’s ...

21c Museum Hotels, a multi-venue contemporary art museum and hospitality brand, has announced the opening of its new property in downtown St. Louis. Travelers and locals alike can enjoy contemporary ...

ST. LOUIS — Located in the heart of downtown you will find the 21C Museum Hotel St. Louis. While the artistic hub is full of entertainment, food, and comfort...they are also full of good news! The ...

Guests take in the red carpet and walls in a stairwell off the main lobby during an open house at the 21c Museum Hotel St. Louis on Tuesday, Aug. 8, 2023. The interior decoration gradually changes ...

The unique hospitality brand, 21c Museum Hotels, will open its 10th hotel this spring — a 10-story lodging in St. Louis with artwork in every room and more than 14,000 square feet of museum exhibition ...

*Refers to the latest 2 years of stltoday.com stories. Cancel anytime. ST. LOUIS — The art-centric 21c Museum Hotel will open its first location in the St. Louis area this spring. The opening will ...