By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Researchers have deciphered the structure of part of the ribosome found ... RNA accounts for just under a third of the entire complex. One reason for this is that the RNA molecules have shortened ...

With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

Now, researchers from Kyushu University have revealed that the smallest known protein-based tRNA-processing enzyme, called ...

And in eukaryotes (life forms with complex cells like ours) there is plenty of extra RNA sticking out of the ribosomes, like the tentacles of a sea anemone. “We think this may provide a ...

Once dismissed as “junk,” a group of RNA molecules has been found to help regrow damaged nerves in mice in new research. The ...

Now, using cryo-electron microscopy, researchers at the University of Tokyo determined the spatial structure of the SpCas9–M-MLV RTΔRNaseH–pegRNA–target DNA complex in multiple states.

Transporting mRNA from the nucleus to the cytoplasm, called mRNA export, relies on protein complexes involving RNA helicases such as UAP56. Despite its near-identical nature, URH49 forms a ...

A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence. Cell. 2024;187(17):4770-4789.e23. McMahon M, et al. Small RNAs with big implications: New insights into H/ACA ...