Long overlooked and underestimated, glial cells—non-neuronal cells that support, protect and communicate with neurons—are ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

How an electrical signal crosses that synaptic gap is not yet entirely understood, but the basic process seems to go like this: a presynaptic neuron receives a message that it has information to ...

Gate Neurosciences to share new data and research on its synaptic function molecules with multiple posters at 2024 ASCP meeting. (2024, May 15).

These results indicate the potential role of EV content as biomarkers in PD. The levels of synaptic proteins in blood exosomes, a specific type of EV, decrease in patients with AD and frontotemporal ...

Huganir says that both functions of SynGAP — enzymatic and the “traffic management” action of a scaffolding protein — may now be important in finding treatments for SynGAP-related neurodevelopmental ...

Tau propagation was also driven by amyloid. In participants with high CSF GAP-43, a high plaque load corresponded with spread through connected brain regions. “Our data support the hypothesis that ...

Synaptic pruning tends to begin when a person is around 2 years old. By the time they are approximately 10 years old, a person’s brain will have removed almost 50% of the synapses that were ...

Gate expects to gain a more nuanced understanding of how dose levels and intervals can be optimized for enduring effects on synaptic function in patients, which further optimizes a next Phase 2 ...