Autoimmune diseases, such as multiple sclerosis (MS), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA), affect millions of people ...

Autoimmune diseases, like multiple sclerosis result when the body's immune system starts to attack its own cells. Regulatory T cells, a subtype of T cells play a critical role in suppressing these ...

Fibrosis is associated with fibroblast activation mediated by transforming growth factor β (TGF-β); therefore, blocking TGF-β signaling pathways is a rational approach to antifibrotic therapy ...

New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies.

Scientists have discovered that starving and then refeeding worms can reveal surprising secrets about aging. When a specific ...

Anita Turk, MD, discusses the unmet needs that still exist in the realm of colorectal cancer treatment and management.

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

Researchers reveal how activating the Egr-1 gene can help alleviate autoimmune inflammation via Foxp3 expression Autoimmune ...

Autoimmune diseases, such as multiple sclerosis (MS), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA), affect ...

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

Growth factor signalling is a cell signalling pathway that regulates the growth and development of an organism. Secreted growth factors bind to transmembrane growth factor receptors to stimulate ...