These data provides further evidence that TRAIL can induce apoptosis (delayed apoptosis at 60 h) via a mitochondrial-independent pathway, whereas etoposide-induced apoptosis is inhibited by ...

Oncogene - TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway Skip to main content Thank you for visiting nature.com.

Targeted induction of programmed cell death or apoptosis via the extrinsic apoptotic pathway represents an unexploited therapeutic strategy to destroy cancer cells. The activation of cell surface ...

Further analysis showed that TCIP1 targets multiple death pathways including popular ones like TNF signaling and the p53 pathway. A bonus of the treatment is that it remains robust even at low ...

Apoptosis pathways. There are two pathways that can initiate apoptosis in a cell: the intrinsic and extrinsic pathways. In the intrinsic pathway cellular stress, once detected, ...

Sree Kant, founder and CEO of BAKX Therapeutics, said, “BAKX brings together the world’s most comprehensive knowledge of the mitochondrial apoptosis pathway with industry leading structure ...