How are individual transmembrane helices in polytopic membrane proteins delivered from the Sec translocon into the lipid bilayer? A new study on the aquaporin-4 water channel shows that they move ...

Seven-transmembrane receptors, which constitute the largest, ... This structure, which corresponds to the inactive receptor, confirms the presence of an anticlockwise bundle of 7TM α helices ...

The current study shows that the spike TMD forms a trimer using a transmembrane helix mode of assembly, seen in this context for the first time. NMR structure of the TMH trimer of SARS-CoV-2 S in ...