Tubulin polyglutamylation is catalysed by Tubulin Tyrosine Ligase-Like (TTLL) enzymes, whose role in neuronal circuit wiring has never been addressed. The enrichment of ttll6 and ttll11 transcripts in ...

imageimageA major unresolved challenge to curing HIV-1 is its presence in the nucleus of infected cells. This study reports on new compounds that specifically block HIV-1 nuclear import by targeting ...