Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...

A personalized neoantigen vaccine may be effective in patients with clear cell renal cell carcinoma, shared David A. Braun, ...

Dr. Ari Hakimi highlighted how tumor profiling and molecular markers are expanding access to precision-based trials for ...

Researchers conducted a population-based cohort study to estimate the prevalence of major thyroid cancer-associated syndromes.

When Toddie Hays decided to participate in nationwide genetics study, she had no idea about the life-changing information ...

A gene called SDR42E1 has been identified as a key player in how our bodies absorb and process vitamin D. Researchers found ...

Scientists report a rare case of coexisting APC and KRAS mutations in a woman with familial adenomatous polyposis and prior endometrial cancer, highlighting a potential genetic synergy in multi-organ ...

Chemotherapy can increase mutation burden and change the cell population structure of normal blood, which contributes to long-term adverse effects such as second malignancies and infertility, ...

The rising median age of people around the world has the same effect, since cancer can take decades to develop and therefore ...

A group led by the Department of Neurosurgery at the Brain Research Institute, Niigata University, has successfully treated a ...

A class of drugs, MDM2 inhibitors, being studied as cancer therapeutics may accidentally damage the protective barriers in the brain and eyes, finds new research in mice.

By understanding this newly revealed mechanism, scientists may now be able to design drugs that disable Hedgehog signaling at ...