Objectives: To assess the efficacy and tolerability of valsartan and valsartan plus hydrochlorothiazide (HCTZ), given alone or as part of a combination regimen with other antihypertensive agents ...

The 4,822-patient study missed statistical significance for a composite primary endpoint of reducing cardiovascular death and total heart failure hospitalisations by 13% compared with valsartan ...

Valsartan 80 mg/day was administered to patients who did not respond to diuretics during heart failure exacerbation in the conventional group (n = 21). Therefore, adding carvedilol to existing ...

Several previous analytical methods have been reported for the determination of sacubitril and valsartan in rat plasma using liquid chromatography (LC) with fluorescence detector 10 and liquid ...