PIM protein kinases have been known for some time as oncogenes that promote lymphomagenesis together with MYC (c-Myc). It is now reported that PIM1 is a coactivator of MYC, and it phosphorylates ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

Vitamin C fuels skin regeneration by unlocking genes that drive cell growth—making aging skin act young again.

Perhaps best known as a immune-system boost or antidote to scurvy, vitamin C has been found to rejuvenate aging skin by ...

Using a 3D human skin model, they showed that C boosts thickness in the epidermal skin layer by activating genes linked to cell growth.

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding ...

Japanese researchers have found that vitamin C can thicken skin by switching on genes that boost skin cell growth, helping reverse age-related thinning. It works by reactivating DNA through a process ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

Shares of Sarepta Therapeutics have plunged again after the drugmaker reported a second death in connection with its gene therapy for muscular dystrophy FILE - The U.S. Food and Drug ...

As we age, our skin naturally becomes thinner and more fragile due to a decline in cell production. Now, researchers have ...