Studies on animal models have shown that the blockade of the CX3CL1/CX3CR1 pathway ameliorates the severity of atherosclerosis, while genetic epidemiology has confirmed that a genetically-defined ...

Ligustroside derived from Ligustrum japonicum shows a significant anti-melanogenesis effect via suppression of the MAPK and PKA/CREB signaling pathways.

Stress hormones activate the β-adrenergic receptor/PKA pathway, while obesity-related signals mainly use the PKD pathway. This suggests that both stress and obesity can fuel pancreatic cancer ...

Bear bile powder inhibits the release of NLRP3 by activating the cAMP/PKA/CREB signaling pathway to treat dextran sulfate sodium-induced colitis in mice Xia & He Publishing Inc.

Further, experimental and clinical settings suggest that the androgen receptor (AR) is implicated on this bone-induced PKA/SPP1 axis. Notably, longitudinal analysis of patients samples revealed an ...