We read with great interest the recent article by Turner et al published in Gut , which evaluated the use of faecal calprotectin to define preclinical stages of Crohn’s disease (CD) in asymptomatic ...
Background RNA 5-methylcytosine (m 5 C) has emerged as a critical epigenetic regulator in cancer biology, yet its role in the tumour immune microenvironment (TME) remains incompletely understood.
Objective The significance of the liver-microbiome axis has been increasingly recognised as a major modulator of autoimmunity. The aim of this study was to take advantage of a large well-defined ...
Dr S Blum, Department of Immunology, Nestlé Research Centre, Vers-Chez-les-Blanc, Ch-1000 Lausanne 26, Switzerland. Email: stephanie.blum-sperisen{at}rdls.nestle.com BACKGROUND AND AIM Intestinal ...
15 Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general ...
2 Institute of Digestive Disease and the Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong ...
Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...
Objective Population-based data are lacking regarding the risk of overall and cause-specific mortality across the complete histological spectrum of non-alcoholic fatty liver disease (NAFLD). Design ...
Correspondence to Dr Michael J Bourke, Department of Gastroenterology and Hepatology, Westmead Hospital, Westmead 2145, New South Wales, Australia; michael{at}citywestgastro.com.au Background and aims ...
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Objective Resection can potentially cure resectable pancreatic cancer (PaC) and significantly prolong survival in some patients. This large-scale international study aimed to investigate variations in ...
Objective HBV infection by blood components is currently prevented in most developed countries by combining sensitive HBV surface antigen (HBsAg) assays, nucleic acid testing (NAT) and in a few of ...