Synopsis If1 inhibition of ATP hydrolysis by the mitochondrial F0F1-ATP synthase is key to stabilize the free F1 subcomplex. If1 is crucial in mitigating mitochondrial depolarizing stress under ...

Clamp loaders are multisubunit complexes that use the energy derived from ATP binding and hydrolysis to assemble ring-shaped sliding clamps onto DNA. Sliding clamps in turn tether DNA polymerases to ...

Eric Jacobsen, the Sheldon Emory Professor of Organic Chemistry in the Department of Chemistry and Chemical Biology at Harvard University, will receive the 2024 Willard Gibbs Medal. The award ...

The aim of the present study was to estimate the true rate k−1 for a pre-phosphorylated WT CFTR channel gating in ATP, as well as to verify disruption of ATP hydrolysis and evaluate effects on B 1 ...

Josiah Willard Gibbs, an American mathematician, first described Gibbs free energy in the 1870s. According to Gibbs, free energy is the total energy of a system that is available to perform useful ...

Keywords: urothelium, bladder, nucleotidases, purine nucleotides, ATP-adenosine triphosphate, ADP, lamina propria (LP), ATP hydrolysis Citation: Aresta Branco MSL, Gutierrez Cruz A, Dayton J, Perrino ...

Including the exergonic synthesis of pyruvate from H 2 and carbon dioxide (Preiner et al., 2020), these sources of carbon-based energy (Table 2) contribute to favorable thermodynamics in 50% of core ...

It is believed that this conformational transition proceeds through a two-step mechanism, with an initial rearrangement of the three cytoplasmic domains of the pump responsible for ATP binding and ...