Recent models of mPTP generally agree that ATP synthase has an essential role in formation of the mPTP. 3,8,9 Moreover, genetic manipulations of the C-subunit of ATP synthase correlate with ...

Bioenergetics: New features of ATP synthase. Science For Life Laboratory. Journal Nature Communications Funder Knut and Alice Wallenberg Foundation (2018.0080), Ragnar Söderberg Foundation (M44 ...

In contrast, R207910 did not have a significant effect on ATP abundance in R207910-resistant M. tuberculosis strains with mutations in subunit c of ATP synthase (BK12 (atpE A63P) 2 and LV13 (atpE ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans ...

ATP is generated within the matrix by an enzyme called ATP synthase. ... The g-subunit rotates 120o clockwise as a result of the conformation change in bDP-subunit causing the ATP-bE subunit to ...

Purification, characterization of ATP synthase complexes from mitochondria of four fungal species. ScienceDaily . Retrieved May 6, 2025 from www.sciencedaily.com / releases / 2015 / 03 ...

With no known treatments for mitochondrial diseases or ATP synthase deficiency, the use of muropeptides as an ATP agonist is a significant discovery. Recent advances in the understanding of the ...

ATP synthase CF1 α subunit protein is a key enzyme for energy metabolism in plant kingdom, and plays an important role in multiple cell processes. In this study, the complete atpA gene (accession no.

Mechanistically, these muropeptides were shown to enter intestinal-cell mitochondria to interact with the F1 complex of ATP synthase, stabilizing the complex and increasing mitochondrial respiration.