Obesity has reached epidemic proportions worldwide, posing a significant burden on people’s health and on healthcare systems. It is a major risk factor for ...

OrganOx, with its system for actively preserving viable donor tissue ahead of a transplant procedure, has raised $142 million to expand its commercial reach and R&D. The company’s metra platform ...

This adipose tissue dysfunction has shown to be associated with a higher risk of CVD and CKD in obesity and metabolic syndrome. However, little is known about the mechanisms underlying this potential ...

Adipose tissue (AT) is a dynamic organ distributed throughout the body with an almost unlimited capacity to expand during obesity. Several distinct depots can be defined by their location, size, ...

HFD-induced adipose tissue dysfunction in wild-type mice was characterized by reduced expression of lipogenic enzymes in white fatty tissue, larger adipocyte sizes, and increased markers of ...

Metabolic dysfunction-associated steatohepatitis (MASH, previously termed non-alcoholic steatohepatitis (NASH)), is a major complication of obesity that promotes fatty liver disease. MASH is ...

The impact of androgens on immune cells in adipose tissue is therefore very interesting considering the high prevalence of insulin resistance and type-2 diabetes among normal weight women with PCOS.

New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May), and published in the International Journal of Obesity, could help explain why type 2 diabetes ...

The process thus goes from maintaining normal adipose tissue function during weight gain, to becoming pathogenic in some cases. When samples of human macrophages were exposed to diabetes-like ...

When the team deleted RalA in the white adipocytes of mice fed a high-fat diet, rodents were both protected from mitochondrial fragmentation and obesity, even when they ate the same high-fat diet as ...