Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely expressed, but its function in breast cancer cells remains unknown.

Triggering of tumour cell apoptosis is the foundation of many cancer therapies. Death receptors of the tumour necrosis factor (TNF) superfamily have been largely characterized, as have the signals ...

Recent research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some ...

Since the time of the ancient Greek physician Hippocrates, cancer has been recognized as being sensitive to heat. Today, this principle forms the basis of hyperthermia treatment—a promising cancer ...

Three-dimensional (3D) cancer models have emerged as pivotal tools in oncology research, offering a more accurate representation of tumor biology compared ...

It is well known that apoptosis is an actively mediated cell suicide process. In contrast, necrosis, a morphologically distinct form of cell death, has traditionally been regarded as passive and ...

Post-translational modifications (PTMs) are essential players in regulating protein functions, including stability, localization, and interactions, and they ...

Blood-based circulating tumor DNA (ctDNA) testing has proven to be insufficient for detecting KRAS mutations in patients with ...

Researchers in Brazil found a molecule in Amazonian scorpion venom that kills breast cancer cells, showing effects similar to chemotherapy drug paclitaxel in lab tests.

Saffron (Crocus sativus L.) is a highly valued spice with potent antioxidant, anti-inflammatory, neuroprotective, and ...

Most shockingly, diquat was dubbed “the worst offender” of the four weed killers. “It is 200 times more chronically toxic ...