Autophagy, a natural cellular process, recycles damaged components, boosting health and anti-aging benefits. Fasting, ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells.

New roles for autophagy genes in cellular waste management and aging Autophagy genes help extrude protein aggregates from neurons in the nematode C. elegans Date: January 4, 2024 Source: Buck ...

They monitored proteins in the men’s blood to see how cold-water plunges affected cellular stress responses, including autophagy, inflammation, and heat shock responses.

VMP1, a protein involved in both autophagy and ER-phagy (removal of damaged ER), is downregulated in pancreatitis. TFEB, a master regulator of lysosomal biogenesis and autophagy, is also decreased.

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

Human genetic and mechanistic studies reveal thousands of pathogenic proteins that may serve as potential targets for small-molecule drugs. Meanwhile, the conventional method of drug discovery ...

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling process and create "garbage bags" to remove proteins.

Autophagy takes place in cell organelles called lysosomes, and these need to be acidic to activate proteases that degrade proteins for recycling into new proteins.

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Proteins are conventionally trafficked and secreted extracellularly via the endoplasmic reticulum-Golgi pathway. Some proteins that bypass this system and use unconventional mechanisms to exit the ...