The enzyme endothelial nitric oxide synthase (eNOS) and its product nitric oxide (NO) play a central role in the control of vascular homeostasis. 9, 10 A significant proportion of circulating MPs ...

Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells (ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary regulator of blood ...

From here, they identified 35 SNPs with a documented role in endothelial cell function. There were a number of criteria for identifying endothelial cell variants, including a known relationship ...

Conclusion Endothelial dysfunction in CHF contributes to the vascular and myocardial remodeling observed in this syndrome. Evidence suggests that African Americans may have, at baseline, a greater ...

Detection of nitric oxide (NO) is important for monitoring air quality because the NO released in the combustion of fossil fuels contributes to acid rain and smog. In medicine, NO is an important ...

Nitric oxide plays a key role in heart health, but supplements for nitric oxide are not backed by much science, says a dietitian.

Paroxysmal nocturnal hemoglobinuria or PNH is a rare and life-threatening blood condition where red blood cells are destroyed by the complement system - part of the innate immune system - causing ...

A key problem contributing to endothelial cell dysfunction is the loss of " redox balance" between harmful molecules called reactive oxygen species (ROS) and helpful molecules like nitric oxide (NO).

Endothelial cell (EC) dysfunction involves reduced nitric oxide (NO) bioavailability due to NO synthase uncoupling linked to increased oxidation and reduced cofactor availability. Loss of endothelial ...