Fragile X disorders include two distinct conditions: fragile X syndrome (the most common single-gene cause of developmental delay and autism) and an entirely separate group of premutation syndromes.

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

PCAF acetylates RAD51, leading to RAD51 dissociation from chromatin and degradation. This highlights a regulatory role for ...