In an article appearing June 23 in the cardiology journal Circulation, the UCSF group reports on the successful treatment of a patient with sudden and severe (acute fulminant) myocarditis using an ...

Scientists have caught the intricate dance of cardiac cells coming together to build a heart, in a mesmerizing new timelapse taken during the development of a mouse embryo. The images were ...

Biocardia Phase 3 CardiAMP-HF Trial of Novel Cardiac Cell Therapy for Ischemic Heart Failure Shows Increased Survival, Decreased Cardiac Events, and Improved Quality of Life at Two Years ...

Calmodulin (CaM) as a ubiquitous Ca2+ sensor interacts with multiple key molecules involved in excitation-contraction (EC) coupling. In the present study, we report that adenoviral expression of a ...

However, important contributions of the immune system to normal cardiac function and the response to injury have recently emerged as exciting areas of investigation. Therapeutic interventions aimed at ...

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...

Researchers hope to enhance graft performance for cardiac cell therapy by exploring new methods to promote cell cycle activation in hPSC-cardiomyocytes.

CaMKII, or Calcium and calmodulin-dependent protein kinase II, is critical to cardiomyocytes, the muscle cells of the heart, where it maintains the balance of calcium.

This affects cardiac electrophysiology, especially Ca 2+ handling, gene expression, intracellular trafficking, mitochondrial processes, energetics, cell-cell coupling, inflammatory reactions, and the ...

Sunitinib and Imatinib Display Differential Cardiotoxicity in Adult Rat Cardiac Fibroblasts That Involves a Role for Calcium/Calmodulin Dependent Protein Kinase II ...