The probe exhibits strong fluorescence responses (up to 900%), sub-second kinetics, and high dopamine specificity without coupling to downstream signaling pathways.

Open in Viewer Figure 1. Cyclic nucleotide signaling and regulation. Localization of fundamental molecules involved in cAMP and cGMP signaling is illustrated. Effector molecules of cAMP and cGMP are ...

Technical Terms c-di-AMP: A cyclic dinucleotide that acts as a second messenger in bacteria, regulating processes such as osmoregulation, cell wall synthesis and stress response.

Transforming Growth Factor Beta Signaling Pathways Publication Trend The graph below shows the total number of publications each year in Transforming Growth Factor Beta Signaling Pathways.

We found that three G-proteins are activated in the downstream GABA cascade, resulting in cAMP elevation. Because the signaling includes stimulating and inhibiting cAMP synthesis, Ciona initiates ...

To explore the enriched biological pathways, we extracted the top 50 enriched KEGG pathways across all nine comparisons (Supplementary Figure 5). Among these, we found that “MAPK signaling ...

Subsequent gene annotation and enrichment analyses were performed to uncover potential molecular mechanisms underlying the relationship between AS and IS. Results: A total of 5,396 consistent DMPs ...

This response involves the stimulation of multiple signaling and transcription pathways that induce hypertrophic remodeling. [1, 2] Potential therapeutic targets aimed at inhibiting these enzymes ...

Calmodulin (CaM), by mediating the stimulation of the activity of two adenylyl cyclases (ACs), plays a key role in integrating the cAMP and Ca2+ signaling systems. These ACs, AC1 and AC8, by decoding ...

Membrane receptors, particularly G protein-coupled receptors (GPCRs), are integral to numerous physiological processes. Precise control of the receptor endocytosis is essential for understanding ...