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Advances in the treatment of heart failure with reduced ejection fraction due to systolic dysfunction are engaging an ever-expanding compendium of molecular signaling targets. Well established ...
The research compares how two bacterial species—Escherichia coli and Mycobacterium tuberculosis—use a signaling molecule called cyclic AMP (cAMP) to control important cellular functions.
ABSTRACT: Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key regulator of heart function. While some CaMKII activity is beneficial, excessive, or persistent, CaMKII can lead to heart ...
The aim of this study was to investigate the molecular and neural mechanisms underlying the regulatory effects of nesfatin-1 on hepatic glucose metabolism and insulin response. Our results suggest ...
Bear bile powder inhibits the release of NLRP3 by activating the cAMP/PKA/CREB signaling pathway to treat dextran sulfate sodium-induced colitis in mice Xia & He Publishing Inc.
Though he did recognize that cAMP and PKA pathways have been studied for half a century, Dr. Zhong presented how his research is focused on the “spatial-temporal activity dynamics in the cyclic AMP ...
BACKGROUND: 3′, 5′-cyclic AMP (cAMP) regulates numerous cardiac functions. Various hormones and neurotransmitters elevate intracellular cAMP (i[cAMP]) in cardiomyocytes through activating GsPCRs ...
The clinical importance of cGMP-PKG pathway is clear; however, a better understanding of underlying mechanisms is necessary for the optimal therapeutic strategy with enhancement of cGMP-PKG signaling ...
Sexual hunger or satiety has been shown to be regulated by cAMP mechanism in dopamine-releasing cells, suggesting that new antidepressants might avoid side effects on libido.
Cyclic adenosine monophosphate (cAMP) is one of the most important signaling molecules in virtually all cell types and organisms. We describe cAMPr, a new single-wavelength cAMP sensor.
By Jeyashree Sundaram, MBA Cyclic adenosine 3,5-monophosphate (cAMP) is a cyclic nucleotide that serves as a vital second messenger in several signaling pathways.
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