Targeting "boot camp" enzyme could fight autoimmune diseases and cancer. Thymus cells generating AIRE proteins, seen in green, which in turn train the surrounding developing T cells seen in red.

‘Boot camp’ enzyme prevents autoimmune conditions WEHI researchers have identified an enzyme in the thymus that is essential for immune T cells to correctly identify threats, safeguarding them ...

Here, the improved enzyme demonstrated a 5- to 10-times better performance compared to its natural precursor. "Our study is a prime example of how we can utilize the mechanisms of metabolism and ...

WEHI researchers have identified an enzyme in the thymus that is essential for immune T cells to correctly identify threats, safeguarding them from going rogue and attacking healthy tissue in the body ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor ...

Intracellular cAMP was measure using the Biotrak cAMP enzyme immunoassay system from Amersham (Arlington Heights, IL, USA). Cells were stimulated for the indicated times and cell extracts were ...

An enzyme in training camp ‘Lactyl-CoA mutase’, which is not found in nature, was specifically developed for efficient synthetic metabolic pathways ...