Non-small cell lung cancer (NSCLC) is one of the deadliest cancers worldwide. In search for new NSCLC treatment options, we screened a cationic amphiphilic drug (CAD) library for cytotoxicity against ...

H1 antihistamines with cationic amphiphilic properties have been shown to possess antitumor effects and were associated with reduced mortality in several cancer types. We aimed to investigate the ...

The impact of cationic amphiphilic antihistamines on patients with lung cancer receiving immunotherapy.. If you have the appropriate software installed, you can download article citation data to the ...

Herein, we compared the efficiency of gene delivery by aerosolization of two types of formulations: (i) BSV163, a branched cationic amphiphilic compound, co-formulated with different DOPE ratios ...

Herein, we report the development of a new series of short cationic amphiphilic peptides with anticancer activity for selective delivery of small interfering RNA (siRNA) and antisense ...

Amphiphilic molecules, which aggregate and encapsulate molecules in water, find use in several fields of chemistry. The simple, additive-free connection of hydrophilic and hydrophobic molecules would ...

Amphiphilic cationic copolymers bind to DNA, facilitating eukaryotic cell transformation, thereby constituting an alternative to viral DNA/RNA vectors (9, 10). Cationic polymers synthesized from 2- ...

Importantly, the potential exists for existing cationic amphiphilic drugs such as antidepressants, antibiotics, antiarrhythmics, and diuretics to be repurposed to engage LCD within therapy-resistant ...

Preparation and Physicochemical Characterization of Drug-Free SqD–NPs Size, PDI, Zeta-Potential, and Morphology Overall, the introduction of anionic, cationic, or PEG moiety into squalene enhanced the ...

The antibacterial and antibiofilm activities of cationic amphiphilic methacrylate polymers against cariogenic bacterium S. mutans were investigated. Cationic homopolymer PE0 and copolymer PE31 ...