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NEW YORK – Researchers at Tulane University recently described a novel latent tuberculosis assay powered by an explosive insect-inspired chemical reaction. Particularly helpful for cases of HIV ...
The association between the monocyte Chemoattractant protein-1-2518A/G polymorphism and the risk of tuberculosis in the Chinese population: A meta-analysis and systematic review ...
Up to date, there is still a lack of clinical and laboratory criteria to identify the cytokine storm. In this review, we referred COVID-19 associated cytokine storm as the patients who are severely ...
Celastrol has been identified as a reactive oxygen species (ROS) elevator that reduces cancer cell proliferation by inhibiting peroxiredoxin (PRDX) activity, albeit with poor selectivity. We describe ...
Celastrol primarily impedes the generation of pro-inflammatory cytokines, nuclear factor-kappa B (NF-κB), and adhesion molecules (Joshi et al., 2016), which all take part in inflammation processes.
Celastrol has been tested in clinical trials for the treatment of chronic inflammatory and autoimmune diseases, and preliminary efficacy was observed. (47) Moreover, its investigation in several ...