If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be ...

Other cell cycle regulators, such as the DNA damage checkpoint kinases and spindle-assembly checkpoint proteins, are also being evaluated as potential new drug targets to improve cancer therapy.

In eight tumors where patients failed immune checkpoint inhibitor (ICI) treatment, Plinabulin + radiation + PD-1 inhibitors demonstrated ...

di- (2-ethylhexyl) phthalate astaxanthin testicular injury apoptosis cell cycle network pharmacology Read this article To access this article, please review the available access options below.

Lung cancer is the second most frequent cancer worldwide, and it accounts for 18% of all cancer-related deaths. Most cases of lung cancer involve non-small-cell lung cancer (NSCLC), in which therapy ...

A cell-cycle checkpoint is a moment in the life cycle of a cell when, following a period of growth and DNA synthesis, a control mechanism determines whether to further grow the cell or terminate it.