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New research from the Sainsbury Laboratory at the University of Cambridge has shed light on how plants precisely control ...
A team of researchers studied the properties of membranes to understand how these cellular structures influenced the chemistry of life on Earth as it began.
The reported cryo-EM imaging of a pentameric ligand-gated ion channel in liposomes as opposed to nanodiscs has both broad implications and contributes valuable methodological advances to the ...
Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...
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AZoLifeSciences on MSNLipid Peroxidation in Lysosomes Unleashes Ferroptosis in TumorsThe duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death.
Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a ...
The middle 1 mM Glu application (III) was preceded by: a 30-s application of 100 μM Mem in the absence of agonist (II), during which Mem entered the cell’s plasma membrane but not the NMDAR; a 1-s ...
These models suggest that action potentials are not purely electrical phenomena but also involve mechanical changes in the cell membrane. The soliton model ... moving along the lipid bilayer. As ...
Structural studies of membrane proteins historically have relied almost exclusively on first removing membrane proteins from the membrane with dispersive agents like detergents. But dispersive agents ...
All cells are surrounded by a cell membrane consisting of a lipid bilayer associated with proteins. The structural basis of the bilayer is formed by phospholipids, which are susceptible to oxidation.
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