Three-dimensional (3D) cancer models have emerged as pivotal tools in oncology research, offering a more accurate representation of tumor biology compared ...

3.3 Mitochondrial dysfunction and apoptosis Apoptosis is an active process of cell death that is regulated by a series of genes, does not release cellular contents to the surrounding environment, and ...

Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptors (TRAILR1 and TRAILR2) are promising targets for cancer therapy: both recombinant TRAIL and monoclonal antibodies ...

The demonstration of distinct apoptosis or solitary cell necrosis in heart failure might prove to be the tip of the iceberg as to the impact of suspended activation of apoptosis.