Orogen Therapeutics, Inc., a private drug discovery company utilizing its proprietary, AI-enabled DNA encoded library (DEL) technology to identify novel chemical matter against medically and ...

An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to ...

An unusual DNA structure may hold the key to treating one of the deadliest cancers affecting women, which claims more than 200,000 lives globally each year.

Prof. Hening Lin brings expertise in enzymes to UChicago, bridging scientists, engineers and doctors to translate research to ...

DNA analysis is considered the gold standard for identifying victims of mass fatalities. But how does it work?

Reactions that alter organic scaffolds by a single atom are already proving useful, but time will tell if they’ll ...

In the ongoing fight against HIV, scientists have taken a new step toward long-term control of the virus. Researchers have ...

Partnering supports novel DEL-screening capabilities Chemspace/Enamine positioned to augment product and service offerings Orogen to gain potential novel therapeutic small molecules Orogen Therapeutic ...

Researchers at Case Western Reserve University have developed an environmentally safer type of plastic that can be used for ...

Accurate prediction of compound-protein interactions (CPI) remains a cornerstone challenge in computational drug discovery. While existing sequence-based approaches leverage molecular fingerprints or ...

Eggs and embryos from people with polycystic ovary syndrome have altered patterns of so-called epigenetic tags, which could ...

Accurately modeling the electronic structure of water across scales, from individual molecules to bulk liquid, remains a grand challenge. Traditional computational methods face a critical trade-off ...