A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases. Proceedings of the National Academy of Sciences , 2019; 201822113 DOI: 10.1073/pnas.1822113116 Cite This Page : ...

Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular ...

In the study, published March 27 in Nature Structural & Molecular Biology, ... Cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) ...

Earl W. Sutherland Jr., former professor and chair of the Department of Pharmacology, led the discovery of cyclic AMP, a cellular signaling molecule responsible for many metabolic processes.He won the ...

Tsukuba, Japan—Cyclic molecules are used in a wide range of applications, including molecular sensing, because they can incorporate specific molecules of interest into their inner cavities ...

THE biologic role of cyclic AMP (adenosine 3′,5′-monophosphate), at least as it is understood today, is shown in Figure 1. After release from an endocrine gland, a hormone is transported to ...

DURHAM, N.C. -- Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic ...