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The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...
And what happens when we remove these complexes from the cytoplasm -- how does this affect neuron function?" ...
When they boosted SmD1 expression in the cells, they found that CHMP7 remained in the cytoplasm, leaving nucleoporins undamaged and TDP-43 in the nucleus where it can regulate gene expression.
Taken together, the data suggest that proteins best known for their role in cell cycle progression have separate functions in the fully differentiated, mitotically inactive neuron.
Camillo Golgi held on to the belief that the brain is comprised of one vast reticulum, long after it was established that neurons are the building blocks of the nervous system.
Scientists mapped every neuron of an adult animal’s brain for the first time It includes all ~50 million connections between nearly 140,000 neurons in the brain of a fruit fly.
Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model of Alzheimer's disease and frontotemporal dementia. These messages ...
Meet the Rosehip Neuron: A Newly Discovered Cell in the Human Brain The neuron is not found within lab mice, possibly explaining why mouse studies often do not translate to human brains ...
A new model of Alzheimer's disease has been proposed, which could speed up efforts to understand and cure the complex condition – while bringing all manifestations of the condition under one unifying ...