Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in ...

Columbia University engineers 3D print self-assembling DNA - using biomolecular code to produce nanoscale devices at scale.

Combined genetic and biophysical characterisation establishes that structure stability and probability of structure formation are key determinants of replisome arrest. Mechanistically, replication ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

DNA nanotechnology has recently provided a novel approach for developing safe, biocompatible, biodegradable, non-immunogenic, and non-toxic drug delivery systems. DNA nanostructures have numerous ...

DNA interstrand cross-links (ICLs) are cytotoxic products of common anticancer drugs and cellular metabolic processes, whose mechanism(s) of repair remains poorly understood. In this study, we show ...