THE demyelinating diseases of the nervous system remain a challenge to scientific investigation and a stumbling block in medical therapy. Comprising an important group of neurologic disorders, they ...

This finding suggests severe peripheral-nerve injury as seen in end-stage neuron loss, regardless of whether the inciting pathophysiological process was axonal or demyelinating.

The term demyelination refers to the loss of the myelin sheath that surrounds and protects axons in the central nervous system.

Chronic inflammatory demyelinating polyneuropathy (CIDP) diagnosis involves a neurological exam, nerve conduction studies, electromyography, cerebrospinal fluid analysis, nerve biopsy, and, in ...

The demyelinating process in NMOSD is only a product of a newly identified and more fundamental disease process: astrocytopathy, or destruction of astrocytes.

The Samanta Lab is aiming to understand the process of demyelination early enough to halt the effects before the disease takes hold of the individual. This is being done through mouse models induced ...

The findings were consistent with a demyelinating process suggestive of multiple sclerosis (MS), Eytan's group said. Which of the following can be a presenting symptom of MS?

NMO, or Devic's disease, is the most likely diagnosis. NMO is an inflammatory demyelinating process that affects the central nervous system. There has been a long debate whether NMO should be ...

Demyelination is the pathological process in which myelin sheaths are lost from around axons (Fig. 1). In the CNS demyelination is usually the consequence of a direct insult targeted at the ...

Patients with rheumatoid arthritis who take a tumor necrosis factor inhibitor do not appear to have a consistent and significant risk for developing a demyelinating disease.

The UAB Center for Pediatric-Onset Demyelinating Disease (CPODD) is one of the founding Pediatric Multiple Sclerosis (MS) Centers of Excellence in the country designated and funded in 2006 by the ...