Cold Spring Harbor Laboratory. (2010, January 20). Novel mouse model of demyelinating disorder. ScienceDaily. Retrieved June 3, 2025 from www.sciencedaily.com / releases / 2010 / 01 / 100114171531.htm ...

Effects of Dock3 on myelin protection in the corpus callosum of a cuprizone-induced demyelinating model. (a and b) Brain coronal sections illustrating a high intensity of LFB (a) and MBP (b) in ...

In the February 1st issue of G&D, Dr. Brian Popko (The University of Chicago) and colleagues describe how mutation of a gene called ZFP191 leads to disordered CNS myelination in mice ...

A study led by Cambridge researchers has shed light on how neural stem cell grafts could help restore myelin in the central ...

18 F-3F4AP is a radiofluorinated version of the multiple sclerosis drug 4-aminopyridine. The tracer, which enters the brain via passive diffusion, binds to demyelinated axons in a similar manner to ...

Importantly, findings from our preclinical studies in demyelination models support the use of 24S-hydroxycholesterol as a biomarker to measure remyelination in certain CNS disorders, ...

As used by the pathologist, the term "demyelination" means that the myelin sheath of certain nerve fibers can no longer be demonstrated in a microscopical section treated with one of a number of ...

Demyelination refers to damage to the myelin around nerves. Myelin coats many nerves in the body, but it can become damaged due to inflammation from viral infections, autoimmune diseases, and ...

The demyelinating disease usually leads to muscle weakness and stiffness, loss of vision, sensation, and coordination, pain, and altered bowel and bladder function.

Demyelination disrupts the conduction of electrical impulses along nerve fibers, ... Novel mouse model of demyelinating disorder. Cold Spring Harbor Laboratory. Journal Genes & Development.