How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health.

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

Several studies have shown that the gene encoding endoplasmic reticulum aminopeptidase 1 (ERAP1) is associated with ankylosing spondylitis (AS). ERAP1 and the closely related ERAP2 are involved in ...

TorsinA is an AAA+ ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

All the latest science news on endoplasmic reticulum from Phys.org. Find the latest news, advancements, and breakthroughs.

The endoplasmic reticulum plays a more important role in type 2 diabetes and its complications than previously believed, new research suggests. To make their discovery, scientists identified ...

We may earn commission if you buy from a link. Why Trust Us? Here’s what you’ll learn when you read this story: Hemifusomes ...

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows that the cells deliberately slow the activity of ...