A dangerous lung disease can go hidden for years, and it affects more women than men. It’s pulmonary hypertension, or high ...

Endothelial dysfunction markers were linked to future disease activity and complications in lcSSc.

Apelin delivered by extracellular vesicles to damaged lungs was found to ease PAH in animal models of the disease, per a ...

A protein called BMPER found at low levels in models has emerged as a PAH treatment target as it may ease disease progression ...

A relatively new therapy used to treat pulmonary arterial hypertension in those with mild to moderate disease was found to be effective at preventing death in those with more advanced disease ...

Pulmonary arterial hypertension (PAH) represents a complex disease with multifaceted pathophysiology involving over 20 identified genetic mutations that can contribute to disease development.

The risk associated with endothelial cell dysfunction was modified by the concentration of LDL cholesterol. In those with LDL levels of 150 mg/dL, for example, the EC-PRS was strongly correlated with ...

Pulmonary hypertension (PH) is associated with endothelial dysfunction. However, the cause of endothelial dysfunction and its impact on PH remain incompletely understood. We aimed to investigate ...

Key takeaways: Pulmonary hypertension appears in 25% to 30% of patients with COPD. There are no approved therapies for patients with this disease combination. Two trials assessing different ...

Pulmonary Arterial Hypertension (PAH) represents a subset of PH characterized by precapillary involvement from the hyperproliferation of pulmonary smooth muscle cells (PASMCs) and pulmonary artery ...

Dietary changes may treat pulmonary hypertension Researchers show restricting two amino acids halts disease progression in rodent models Date: May 2, 2024 Source: University of Pittsburgh Summary ...