A dangerous lung disease can go hidden for years, and it affects more women than men. It’s pulmonary hypertension, or high ...

Endothelial dysfunction markers were linked to future disease activity and complications in lcSSc.

Apelin delivered by extracellular vesicles to damaged lungs was found to ease PAH in animal models of the disease, per a ...

A protein called BMPER found at low levels in models has emerged as a PAH treatment target as it may ease disease progression ...

Background—Pulmonary hypertension (PH) and collagen metabolism abnormalities are prevalent in patients with heart failure with preserved ejection fraction (HFpEF). Peripheral endothelial dysfunction ...

This review not only synthesizes current knowledge on endothelial dysfunction in cSVD but also critically evaluates the diagnostic and prognostic utility of emerging endothelial biomarkers and ...

Keywords: pterostilbene, pulmonary arterial hypertension, endothelial-to-mesenchymal transition, high mobility group AT-hook, SNAI, twist Citation: Wang J, Zhang Y, Liu J, Jiang F, Cui X and Lu W ...

BACKGROUND: Pulmonary hypertension, characterized by vascular remodeling, currently lacks curative therapeutic options. The dysfunction of pulmonary artery endothelial cells plays a pivotal role in ...