NO production by neuronal nitric oxide synthase (nNOS) requires calmodulin and is enhanced by the chaperone Hsp90, which cycles dynamically with the enzyme. The proteasomal degradation of nNOS is ...

Integrated metabolome and transcriptome analysis reveals salicylic acid and flavonoid pathways’ key roles in cabbage’s defense responses to Xanthomonas campestris pv. campestris ...

Calmodulin (CaM) kinase is a ubiquitous serine/threonine kinase that has recently been shown to modulate the release of activator Ca 2+ during excitation-contraction coupling in ventricular myocytes.

OC Rescue Mission sees a pathway for homeless in the building trades Bryan Crain, head of the faith-based OC Rescue Mission, sees opportunity to expand its training program to carpentry, drywall ...

Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase.

Hui Mo‘olelo Mural Project at University of Hawaiʻi Maui College, Presented by Maui Public Art Corps with artist Solomon Enos ...

The Maui Metropolitan Planning Organization invites the Hāna community and the public to attend the final in-person community meeting for the Hāna Community Pathway Study on Monday, June 23, 6: ...

In cancer cells, apoptosis induced by the extrinsic pathway complements that induced by the intrinsic pathway, so targeting death receptors is considered a useful new therapeutic approach.

Unraveling structural transitions and kinetics along the fold-switching pathway of the RfaH C-terminal domain using exchange-based NMR ...

Endothelial nitric oxide synthase (eNOS) is the primary physiological source of nitric oxide (NO) that regulates cardiovascular homeostasis. Historically eNOS has been thought to be a constitutively ...