The researchers report in the journal Nature Communications that the globally dominant human norovirus GII.4 strain invades gastrointestinal cells via an unexpected mechanism. The viral strategy ...

Norovirus, or "winter vomiting bug", is an extremely contagious virus that causes gastrointestinal illness in humans.

Two capsid structures were also identified in the human norovirus VLP, but it has not elucidated the switching mechanism of the structure yet.

In this Review, we discuss the molecular and structural mechanisms that facilitate the persistence of noroviruses in human populations.

Human norovirus will not infect any of the species typically used in biomedical research, such as mice, rats or rabbits. Human norovirus won't grow even in human cells in petri dishes.

Can dogs get norovirus from humans? Yes, based on indications from two research studies, it appears that dogs can get infected by norovirus from humans.

"It is exciting to now have human monoclonal antibodies that neutralize many norovirus variants," added Estes. Story Source: Materials provided by Vanderbilt University Medical Center.

In a major step forward in the development of a norovirus vaccine, researchers discover a neutralizing antibody that can bind to a highly conserved epitope.

Cocrystal plans to initiate a human norovirus challenge study in 2025 in the U.S. to evaluate CDI-988 as a potential prevention and treatment of norovirus infection.

The researchers report in the journal Nature Communications that the globally dominant human norovirus GII.4 strain invades gastrointestinal cells via an unexpected mechanism.