However, on the pathological side, excessive or dysregulated NETs can cause hyperinflammation, hepatocyte injury, promote tumor metastasis, lead to fibrillation, and obstruct small blood vessels, ...

Accumulating studies have shown that lncRNAs are encapsulated by extracellular vesicles (EVs), and can stably exist in peripheral blood, which makes them novel non-invasive tumor marker (19). EVs are ...

Schechter, M.C., et al. (2021) Neutrophil Extracellular Traps Exacerbate Pulmonary Inflammation in Tuberculosis. JCI Insight, 6, e149871.

Background: Recently, we have demonstrated that red blood cells (RBCs) from individuals with type 2 diabetes (T2D-RBCs) induce endothelial dysfunction via upregulation of arginase-1 in RBCs. However, ...

Independent of etiology, hemolytic diseases are associated with thrombosis, inflammation and immune dysregulation, all together contributing to organ damage and poor outcome. Beyond anemia and the ...