New research reveals how exercise transforms muscles into communication hubs that release beneficial molecules throughout the ...

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.

Skeletal muscle could play a role in the pathophysiology of insulin dysregulation in patients with Friedreich’s ataxia (FA), a study found.

This is the percentage of the body's mass that is fluid. The human body is 50 to 75 percent water, and how much you have at ...

The discoveries of this study hold substantial importance, as they shed light on the interplay between genetic attributes and environmental conditions in shaping the insulin-signaling network within ...

They say the authors share compelling evidence that sheds light on the interplay between genetic attributes and environmental conditions in shaping insulin signaling in skeletal muscle – a ...

Skeletal muscle has a critical role in the regulation of the energy balance of the organism, particularly as the principal tissue responsible for insulin-stimulated glucose disposal and as the major ...

Abstract The secreted protein isthmin-1 (Ism1) mitigates diabetes by increasing adipocyte and skeletal muscle glucose uptake by activating the PI3K-Akt pathway. However, while both Ism1 and insulin ...

Insulin flux across the endothelium to muscle cells is a rate‐limiting process influencing insulin‐mediated lowering of blood glucose. Here, we demonstrate that Notch signaling in EC s regulates ...