Although the heterotrimeric receptors for interleukin-2 (IL-2) and IL-15 have two subunits in common, these cytokines have contrasting roles in adaptive immune responses. Understanding the biology ...

A new study shows how IL-2’s flexible structure governs its effects on the immune system, providing crucial information for harnessing its therapeutic potential.

IMAB362 plus zoledronic acid (ZA) and interleukin-2 (IL-2) in patients (pts) with advanced gastroesophageal cancer (GEC): Clinical activity and safety data from the PILOT phase I trial.